Detection of deviations in the composition of blood serum using microstructural fibers
Yulia S. Skibina2, Svetlana S. Konnova1,2, Aleksey Yu. Gryaznov2, Pavel A. Lepilin1,2, Anastasia A. Zanishhevskaya1,2, Andrei A. Shuvalov2, Valery V. Tuchin1
1 Saratov State University, Russia
2LLC SPE “Nanostructed Glass Technology”, International Research and Education Center “Structural Nanobiophotonics”, Russia
Abstract
The principle of using microstructural waveguides is based on the detection and identification of biological molecules by the spectra of radiation passing through a hollow core filled with the material under study in the wavelength range from 200 nm to 1100 nm. The advantages of optical biosensors include high sensitivity, short response time, non-contact, and low influence of electrical noise. In this study, blood sera from volunteers (healthy and sick) were studied by using microstructural waveguides. As a result, differences in the spectral characteristics of blood serum in sick and healthy volunteers were shown. In this regard, we believe that this method can be used for the identification and rapid diagnosis of various diseases, but this work requires a larger number of volunteers from the experimental and control groups.
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Svetlana S. Konnova
LLC SPE "Nanostructed Glass Technology"
Russia
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