Experimental Assessment of Dual-Wavelength Photoplethysmographic Signal Quality in a Laboratory Mouse
Aleksandr O. Kashichkin1, Daria A. Zlatogorskaya2, Ivan V. Fedosov1; 1Department of Optics and Biophotonics, Saratov State University, Saratov, 410012, Russia; 2Department of Biology, Saratov State University, Saratov, 410012, Russia
Abstract
Prolonged photoplethysmographic (PPG) recording of cerebral signals in awake laboratory mice is complicated by insufficient sensor–tissue contact and motion artifacts. This study aimed to develop a detachable magnetic platform for reproducible positioning of a dual-wavelength module on the animal’s head and to perform a preliminary assessment of the recorded signal quality. A group of male mice was studied. Optical signals in the red and infrared channels were recorded during recovery from anesthesia and in the awake state. Variations in cerebral pulse-wave frequency were analyzed during the recovery period. These findings demonstrate the technical feasibility of prolonged acquisition of periodic optical signals.
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Aleksandr Kashichkin
Saratov State University
Russia
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