In vivo study of skin optical clearing in rats with alloxan diabetes of varying duration
Daria K. Tuchina,1, 2 Alla B. Bucharskaya3, Valery V. Tuchin1,2,4
1Institute of Physics and Science Medical Center, Saratov State University, Saratov, Russia
2Laboratory of Laser Molecular Imaging and Machine Learning, Tomsk State University, Tomsk, Russia
3Saratov State Medical University, Saratov, Russia
4Institute of Precision Mechanics and Control, FRS “Saratov Scientific Centre of the RAS”, Saratov, Russia
Abstract
In the in vivo experimental and computational studies the effect of aqueous 70% glycerol solution on the skin of rats with model (alloxan) diabetes of different durations was studied, namely, the time dependences of the light attenuation coefficient in the skin of rats with model diabetes in vivo were obtained, the effectiveness and rate of optical clearing of the skin in vivo was assessed using OCT.
Speaker
Daria K. Tuchina
Saratov State University
Russia
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