A Compact Device for Non-Invasive Sleep Monitoring
A.O. Kashichkin, I.V. Fedosov; Saratov State University, Saratov, Russia
Abstract
Sleep staging is critical for many applications in neurology and sleep medicine including Alzheimer disease, sleep apnea and traumatic brain injuries treatment. Currently the only way for accurate sleep staging requires EEG recording. For human subject it is related with fixation on numerous electrodes for whole sleep period that is not comfortable and could be performed only with trained clinical personnel. For laboratory mice EEG recording requires implantation of the electrodes that biased preclinical researches and increases death rate. This significantly limits the possibility of long-term and safe sleep studies on animal models. The aim of this study is to develop a non-invasive method for diagnosing sleep that provides safe and accurate measurement of vital signs as well as access to raw physiological data. A microcontroller with two sensors was employed to record heart rate, blood oxygen saturation, and movement based on accelerometer data. These signals can be used for non-invasive sleep staging. A device was developed and tested on a human subject. The device successfully recorded physiological parameters, confirming its operability and ability to capture state changes. The developed device enables non-invasive recording of physiological parameters and can be applied for sleep diagnostics in mice. Its uniqueness compared to commercial smartwatches and pulse oximeters lies in the ability to acquire raw physiological data in a convenient form factor, making it a promising tool for further laboratory sleep research in both animals and human subjects.
Speaker
Aleksandr
Saratov State University
Russia
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