Tissue differentiation based on analysis of changes in attenuation coefficient under mechanical stress estimated with optical coherence tomography
Evgeny P. Sherstnev1, Alexander A. Moiseev1, Grigory V. Gelikonov1; 1Institute of Applied Physics of the Russian Academy of Sciences, Nizhny Novgorod, Russia
Abstract
This study is devoted to distinguishing between samples with different mechanical properties by analyzing the changes in the attenuation coefficient of these samples during their axial deformation. Experimental work was carried out to measure the dependence of the attenuation coefficient on the stress applied to the sample. The depth-resolved method was used to estimate the attenuation coefficient of samples from optical coherence tomography data. Shore hardness was measured to evaluate the mechanical properties of the studied samples. An approach based on two parameters (the average attenuation coefficient of the sample and the slope parameter, which characterizes the changes in the attenuation coefficient during axial deformation of the sample) to distinguishing between samples is proposed. The proposed approach can be used to obtain additional information in elastographic measurements based on optical coherence tomography.
Speaker
Evgeny P. Sherstnev
Institute of Applied Physics of the Russian Academy of Sciences, Nizhny Novgorod, Russia
Russia
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