SERS sensor systems for the detection number of actual analytes in bio- and environment samples: emerging problems and their solution
Mariia V. Samodelova1, Igor K. Solontsov1, Olesya O. Kapitanova1, Irina A. Veselova1;
1Lomonosov Moscow State University, Moscow, Russsia
Abstract
Surface-enhanced Raman spectroscopy (SERS) is a highly sensitive method for analyzing chemical substances that does not require sample pretreatment. Existing sensors based on noble metal nanoparticles demonstrate low efficiency due to insufficient affinity for the substances being analyzed and the influence of matrix effects in real samples. Plasmonic composites with adjustable optical properties and components that minimize the matrix effect have been proposed to address this issue. The developed systems include a polymer matrix, silver nanoparticles, and modifying additives that allow for achieving a specific effect, such as increasing the sorption of the analyte, suppressing the fluorescent background, and increasing detection sensitivity through chemical interactions, depending on the object under study and the tasks at hand.
This work was supported by the RSF [grant number 23-13-00276].
Speaker
Mariia Samodelova
Lomonosov Moscow State University, Department of Chemistry
Russia
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