Dual-template imprinted polyaniline synthesized by design of experiments

Abstract

The creation of synthetic polymers capable of mimicking recognition processes characteristic of nature is an important area of research. One of the strategies used to create materials with recognition Similar to antibodies and biological receptors is molecular imprinting. The main advantages of molecular imprinted polymers include their high specificity with respect to the analyte used in the imprinting process, chemical and physical stability, and low cost of synthesis. Aniline and its derivatives are popular monomers used to form the polymer network of molecular imprinted polymers. Self-assembly of aniline in an aqueous environment leads to the formation of polyaniline. The material is characterized by environmental safety, low cost and long-term stability.

In this paper, we investigated the possibility of design dual-template imprinted polyaniline using quercetin and horseradish peroxidase as templates. The response surface technique was used to efficiently select optimal conditions for a complex multifactorial system. An imprinted polyaniline layer was obtained on the surface of a microtiter plate and used for solid-phase extraction of analytes. The resulting material has a specificity for both low- and high-molecular compounds (imprinting factor was 2.3 for quercetin and 24.6 for horseradish peroxidase, respectively). The creation of a dual-template imprinted materials has not been previously described.

Speaker

Victoria Gorlo
Saratov State University
Russia

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