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EFFECT OF LASER POWER ON THE TIME DEPENDENCE OF THE SAMPLE SELF-ASSEMBLY PROCESS UNDER THE ACTION OF RADIATION

Mikhail S. Savelyev1,2, Pavel N. Vasilevsky1, Ekaterina P. Otsupko1, Alexander Yu. Gerasimenko1,2; 1National Research University of Electronic Technology, MIET, Zelenograd, Moscow, Russia; 2I.M. Sechenov First Moscow State Medical University, Sechenov University, Moscow, Russia

Abstract

A study was conducted on the formation of a composite from an aqueous dispersion of albumin, chitosan, collagen, eosin Y, single-walled carbon nanotubes (SWCNTs) and reduced graphene oxide (RGO) using laser self-assembly. A pulsed mode with a frequency of 30 kHz, a pulse duration of 100 ns and a wavelength of 1070 nm was used. Temperature control in the irradiation zone at a power of less than 500 mW made it possible to determine the conditions for stable formation of the composite.
The phase transition is observed at a temperature of 40–50 °C. During the formation of the composite, a sharp decrease in transmittance by five times is noted. The obtained material has a specific conductivity of 140 mS/cm, and the inclusion of biopolymers ensures high biocompatibility, which is confirmed by cell proliferation, which exceeded the control sample on a cover glass.
The proposed material can be used to create neuroimplants designed to restore communication between neurons through a damaged area of tissue and block pain signals. In such systems, feedback between the stimulated area and the neurostimulator is important. The structure of neurointerfaces can be based on the principles of biological systems, where carbon components act as artificial neurons, and the use of biopolymers allows simulating tissue with high biocompatibility.
The work was carried out with the financial support of the Ministry of Education and Science of Russia within the framework of a major scientific project (Agreement № 075-15-2024-555 from 25 April 2024).

Speaker

Savelyev Mikhail Sergeevich
National Research University of Electronic Technology; I.M. Sechenov First Moscow State Medical University
Russian Federation

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