Quantum bioinformatics based on DNA and quadruplexes

Abstract

The role that informatics plays in modern science is due to the explosive development of computer technologies. A new and more general direction is to consider bioinformatics as informatics on the bases of nanobioelectronics and biocomputer technologies. DNA molecular is an important example of data storage and biocomputing. Performing millions of operations simultaneously DNA – biocomputer allows the performance rate to increase exponentially. The limitation problem is that each stage of paralleled operations takes a very long time. To overcome this problem can nanobioelectronics. The new branch of nanobioelectronics based on quadruplex quantum calculations is discussed. It is shown that quantum evolution under consideration leads to the solution of large systems of linear algebraic equations and their eigen value problem.
Such processes as DNA quantum cellular automata dynamics , DNA charge transport , Bloch oscillations, soliton evolution, polaron dynamics, breather creation and breather inspired charge transfer are discussed. The supercomputer simulation of charge dynamics at finite temperatures is presented. Different molecular devices based on DNA are considered. These make the solution of quantum bioinformatics problems based on DNA technologies.

Speaker

Victor D. Lakhno
Institute of Mathematical Problems of Biology RAS – the Branch of Keldysh Institute of Applied Mathematics of Russian Academy of Sciences
Russia

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