Effect of upconversion nanoparticles on refractometric properties of tumor tissue
Kovalenko V A,1 Kochubey V I,1 Navolokin N A,2 Mylnikov A M,2 Yanina I Yu1,3
1Saratov State University, 83 Astrakhanskaya str., Saratov 410012, Russian Federation,
2Saratov State Medical University named after V.I. Razumovsky, 112, B. Kazachya St.,
Saratov 410012, Russian Federation.
3Tomsk State University, 36 Lenin’s av., Tomsk 634050, Russia
Abstract
This paper presents the results of experimental measurements of refractive indices at various
wavelengths in the visible and near IR ranges (480-1550 nm) for tumor tissue (model alveolar liver
cancer), altered tissue after application of upconversion nanoparticles NaYF4 with a solution of human
serum albumin (HSA) and photodynamic dye (Cy3)). The refractive index (RI) was measured on a multi-
wave Abbe refractometer DR-M2/1550 (Atago, Japan) using interference filters for the spectral range of
480–1550 nm. An analysis of the obtained dispersion dependences was carried out.
Speaker
Kovalenko V A
1 Saratov State University
Russia
Discussion
Ask question
