Investigation of the effect of the tracheal optical properties on the possibility of spectral assessment of the level of its blood supply in vivo
Anna A. Krivetskaya1,2, Daniil M. Kustov1, Vladimir D. Parshin3, Mikhail A. Ursov3, Alexander V. Mariyko3, Vladimir V. Levkin4, Sergey S. Kharnas4, Tatiana A. Savelieva1,2;
1Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow, Russia;
2Institute of Engineering Physics for Biomedicine, National Research Nuclear University MEPhI, Moscow, Russia;
3NMRC PhPI M.H, Moscow, Russia;
4Department of Faculty Surgery No. 1, I.M. Sechenov First Moscow State Medical University, Moscow, Russia
Abstract
Introduction: There is no common procedure for intraoperative assessment of the state of tracheal wall. Therefore, it is necessary to put into practice and make approbation of the methodology for the desired aim.
Purpose: The purpose of this work is devoted to the presentation of an intraoperative method for evaluation of the blood supply to tracheal tissues.
Materials and Methods: The possibility of intraoperative assessment as well as the influence of the variation of the optical properties of tracheal layers were investigated using Monte-Carlo simulation. The evaluation of the tracheal blood supply was performed with diffuse reflectance spectroscopy using “LESA-01-BIOSPEC” spectrometer.
Results: As a result of this study, the dependences of the magnitude of diffusely scattered signal were obtained with varying thickness of the tracheal layers and with different degrees of saturation of the tissues of the suprachondrium with oxygen. An intraoperative assessment of saturation by diffuse scattering spectroscopy was performed before tissue dissection, after removal of the damaged part of the trachea and after anastomosis.
Conclusion: According to the results of this study, saturation assessment by diffuse scattering spectroscopy can be used to assess the condition of tracheal tissues by the level of blood supply in clinical conditions in real time.
Speaker
Anna Krivetskaya
1 Prokhorov General Physics Institute of the Russian Academy of Sciences, Moscow, Russia 2 Institute of Engineering Physics for Biomedicine, National Research Nuclear University MEPhI, Moscow, Russia
Russia
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