Assessment of blood microcirculation and oxidative metabolism of biological tissue in limb vessels during traumatic operations using laser Doppler flowmetry and fluorescence spectroscopy
A.D.Usanov1, M.V. Prigorodov2, S.V. Kapralov2, A.V. Skripal1; 1Saratov State University,Saratov, Russia; 2Saratov State Medical University, Saratov, Russia
Abstract
The results of measurements of the blood microcirculation index and the index of oxidative metabolism of the patient during traumatic operations using laser Doppler flowmetry and fluorescence spectroscopy are presented. The study was conducted on 12 patients who underwent surgery under combined anesthesia. The microcirculation of the skin and the activity of tissue coenzyme - reduced nicotinamide adenine dinucleotide - were studied by laser Doppler flowmetry and fluorescence spectroscopy using a portable laser blood microcirculation analyzer "LASMA PF-3" on the distal phalanx of the middle finger of the hand throughout the operation. According to laser Doppler fluorometry and fluorescence spectroscopy, combined anesthesia causes an increase in the microcirculation index, which reaches its maximum during the traumatic stage of the operation, with a gradual return to preoperative values by the end of the operation and combined anesthesia. The indicator of oxidative metabolism during the entire operation experienced jumps with a tendency to increase and by the end of the operation and anesthesia reached a maximum value of 5.15 at a norm of 3.6-4.1, which may indicate violations of redox processes.
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A.D. Usanov
Saratov State University
Russia
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