Studies of solder compositions with nanoparticles for laser welding of damaged tissues

Abstract

This work presents the results of studies of solder compositions with nanoparticles increasing the tensile strength: magnetite, aluminum, nickel and carbon nanotubes for laser welding of biological tissues. These particles absorb laser radiation in the near infrared range, so that the solder under the influence of laser radiation changes from liquid to solid state. This method helps to avoid the appearance of postoperative scar and reduce the time of surgery in the case of large areas of tissue. For the experiments the solder was made by mixing in distilled water bovine serum albumin, indocyanine green and nanoparticles of the selected type. The effectiveness of obtained solders was experimentally tested on skin and vessels of laboratory animals ex vivo. The dissected tissues were welded by diode laser with a wavelength of 810 nm at 55 °C. The addition of nickel did not make a significant difference in the strength of the laser connections compared to the solder without nanoparticles. The strength for solders with the addition of 100 nm aluminum nanoparticles showed strength values equivalent to those for carbon nanotubes. Thus, the considered types of nanoparticles have the potential to be used in the composition of nanomaterials for laser repair of large tissue defects.
This work was financed by the Ministry of Science and Higher Education of the Russian Federation within the framework of state support for the creation and development of World-Class Research Centers "Digital biodesign and personalized healthcare" №075-15-2022-304.

Speaker

Uliana Kurilova
I.M. Sechenov First Moscow State Medical University, National Research University of Electronic Technology
Russia

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