Raman spectroscopy for assessing the effect of bone mineral component on animal bone tissue
Yuri D. Ityaksov1, Elena V. Timchenko1,2, Pavel E. Timchenko1,2, Oleg O. Frolov1, Elena V. Pisareva1, Mikhail Yu. Vlasov1,2, Larisa T. Volova2, Eizons M. Tchang1, Yves N. Lemba1; 1Samara National Research University named after academician S.P. Korolev, Samara, Russia; 2Samara State Medical University, Samara, Russia.
Abstract
The aim of the work was to use the Raman spectroscopy method to assess the effect of the mineral bone component on the bone tissue of animals.
The study was conducted on 15 pigs of the Livenskaya breed.
As a result of the studies, it was found that the administered dose of MCC (100 mg per kg of weight) of the drug does not affect the composition of the bone tissue of animals, which is clearly visible in the Raman spectra. It was found that in the entire studied spectral range from 380-1900 cm-1, no significant spectral changes are observed between the studied groups.
The results obtained are confirmed by the results of biochemical analysis.
Speaker
Ityaksov Yuri Dmitrievich
Samara National Research University named after Academician S.P. Korolev
Russian Federation
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