APPLICATION OF OPTICAL METHODS IN THE STANDARDIZATION OF COLLAGEN-CONTAINING HYDROGEL FOR 3D BIOPRINTING OF SUPPORTING AND CONNECTIVE TISSUES
Elena V. Timchenko, Nikolai A. Ryabov, Oleg O. Frolov, Pavel E. Timchenko, Larisa T. Volova, Sergej S. Ivanov.
Abstract
The paper presents the results of the application of optical methods in the standardization of collagen-containing allogeneic hydrogel produced at the Biotech Research Institute (Samara, Russia) from bioimplants of the Lioplast® trademark in comparison with the hydrogels available on the market from Rokit and Cellink companies. The Raman spectroscopy method was used as the main research method. An additional research method was the method of IR Fourier spectroscopy. As a result of the conducted research using optical methods, it was found that the collagen structure is completely preserved in the composition of the allogeneic hydrogel produced at the Biotech Research Institute (Samara, Russia). Hydrogels of the imported production companies ROKiT and Cellink also have a similar spectral composition.The results obtained can be further used as a rapid assessment and standardization of collagen-containing hydrogel with the addition of various components for personalized 3D bioprinting.
Speaker
Sergey Ivanov Sergeevich
S.P. Korolyov Samara National Research University
Russia
Report
File with report
Discussion
Ask question
