Engineering multifunctional particles from drug delivery systems, bioreactors, biosensing and bioimaging applications

Abstract

Multifunctional materials hold great promise in several biomedical applications, such as drug delivery, cell biology, biosensing and bioimaging. In this regard, the multifunctional materials which are active in the visible and near-infrared (NIR) regions and can be physically guided (laser light, magnetic field, ultrasound etc.) become even more critical for the improving examined biomarkers, cells, and organisms. This lecture will cover the topic the fabrication of targeted drug delivery carriers for in vivo application using fluorescence tomography, application of multicompartment particles for enzyme catalysed chemical reaction by measuring chemiluminescence. Throughout the lecture we will discuss how to isolate small extracellular vesicles by magnetic beads and characterize vesicle membrane receptors by dye labelled molecules with the help of flow cytometry.

This work was supported by the Russian Science Foundation (RSF) grant N 23-74-00022.

Speaker

Alexey Yashchenok
Skolkovo Institute of Science and Technology
Russia

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