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Investigation of the effect of prolonged exposure to OCA-aerosol (glycerin/propylene glycol) on rat plasma by Raman spectroscopy.

Arina A. Sokova 1, Ekaterina N. Lazareva 1,2, Alexander E. Polozhenkov 3, Artem M. Mylnikov 3, Alla B. Bucharskaya 1,2,3, Valery V. Tuchin 1,2,4; 1 Saratov State University, Saratov, Russia; 2 Tomsk State University, Tomsk, Russia; 3 Saratov State Medical University, Saratov, Russia; 4 Institute of Precision Mechanics and Control RAS, Saratov, Russia.

Abstract

An urgent problem of our time is the replacement of tobacco smoking with the use of devices with steam smoking mixtures. However, scientists have already proved that their use also has a negative effect on the human body causing irreversible changes [1]. Raman spectroscopy (RAMAN) is one of the methods that allows analyzing the molecular composition of a substance, in particular blood and its components [2]. When inhaling "smoking mixtures", many chemical compounds enter the bloodstream, including glycerin and propylene glycol [1,3]. When smoking, from 3 to 10% of active substances accumulate in the blood, which have a negative effect on the body. Since one of the functions of blood is transportation, it is it that carries chemical compounds harmful to the body, therefore, the object of research in this work is plasma, which makes up most of the volume of blood.

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Arina A. Sokova
Saratov State University
Russia

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