Сhanges in the mechanisms of microcirculation regulation during direct optical generation of singlet oxygen
Lyubov V. Eratova, Irina N. Makovik
Orel State University
Abstract
The article is devoted to the study of the effect of laser-induced singlet oxygen (SO) on the parameters of the microcirculatory system (MCS). To study the mechanisms of regulation of the MCS blood flow activated during SO generation, a multifunctional laser research complex combining methods of laser Doppler flowmetry (LDF) and fluorescence spectroscopy was used. The groups were formed according to the dominant change between the stages in the active mechanisms of vascular tone regulation. As a result of the study, it was found that exposure to SO leads to a dominant increase (p<0.05) in the amplitudes of blood flow oscillations of endothelial and neurogenic genesis. Thus, we can say that SO selectively affects small arteries and arteriovenous anastomosis and redistributes blood flow.
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Lyubov Eratova
Orel State University
Russian
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