Modeling of Thermo-Optical Properties of Ferromagnetic Plasmon Nanocomposites for Laser Local Hyperthermia
A.N. Yakunin,1 S.V. Zarkov,1 Yu.A. Avetisyan,1 G.G. Akchurin,1,2 V.K. Belyaev,3 V.V. Rodionova,3 V.V. Tuchin,1,2,4,5; 1Institute of Precision Mechanics and Control, FRC “Saratov Scientific Centre of the Russian Academy of Sciences”, Saratov, Russia
2Saratov State University, Saratov, Russia; 3Immanuel Kant Baltic Federal University, Kaliningrad, Russia; 4Tomsk State University, Tomsk, Russia; 5Bach Institute of Biochemistry, FRC “Fundamentals of Biotechnology of the Russian Academy of Sciences”, Moscow, Russia
Abstract
A theoretical study was made of the influence of the structure and optical properties of the components of ferromagnetic nanocomposites based on gold and cobalt ferrite nanospheres on the absorption spectrum upon irradiation with laser light. The application of such composites for local laser hyperthermia of biological tissues, including cancerous tumors, has been shown to be promising. Additional advantages are provided by the possibilities of implementing technologies for the targeted delivery of composites and the concentration of heat sources due to plasmonic field amplification. It is found that a continuous CFO layer leads to a 1.5-fold increase in the absorbed power of the composite and a simultaneous shift of the resonance from the point λ=526 nm to the point λ=600 nm. The form of the obtained spectral curve, in general, corresponds to the experimental results of measuring the suspension extinction. A non-trivial effect of the redistribution of absorbed power was also found, which consists in the fact that its value decreased in GNS and increased significantly in CFO.
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Alexander N. Yakunin
Institute of Precision Mechanics and Control, FRC “Saratov Scientific Centre of the Russian Academy of Sciences”, Saratov
Russia
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