Development of a method for measuring the volume fraction of water using a combination of optical coherence tomography and high-frequency ultrasound
Yu.I. Surkov, 1,2 I.A. Serebryakova,1,2, E.A. Genina, 1,2
1 Saratov State University, Saratov, Russia
2 Tomsk State University, Tomsk, Russia
Abstract
The work is devoted to the development of a combined method of optical coherence tomography (OCT) and high-frequency ultrasound (ultrasound) for measuring the thickness-average hydration and the group refractive index. The presented method is based on a spatially consistent measurement of the acoustic and optical thicknesses of a biological sample and further calculation of the volume fraction of water according to a mathematical model. Experimental examples of measuring the hydration index of gelatin phantoms are given. There is a potential possibility of transferring the method for in vivo studies of biological tissues with a thickness of about 1 mm.
The reported study was funded by the grant of RFBR (#20-52-56005) and the grant under the Degree of the Government of the Russian Federation No. 220 of 09 April 2010 (Agreement No. 075-15-2021-615 of 04 June 2021).
Speaker
Yury I. Surkov
Saratov State University, Saratov, Russia
Russia
Discussion
Ask question
