Asymmetry analysis for automated diagnostics of maxillary sinus pathologies in digital diaphanoscopy
E.O. Bryanskaya,1 M.Yu. Kirillin,2 V.V. Dremin,1,3 A.V. Dunaev,1,
1 Orel State University named after I.S. Turgenev, Komsomolskaya St. 95, Orel, Russia
2 Institute of Applied Physics RAS, 603950 Nizhny Novgorod, Russia
3 College of Engineering and Physical Sciences, Aston University, Birmingham B4 7ET, UK
Abstract
Digital diaphanoscopy is a promising technique for screening maxillary sinus pathologies owing to non-invasiveness, safety and simplicity in operation. This technique is based on illumination of maxillary sinuses at wavelengths of 650 and 850 nm with a custom-designed LED applicator inserted into oral cavity subsequent registration of diaphanograms by a CMOS-camera, and further digital processing. Presence of maxillary sinuses pathologies, primarily of inflammatory origin, increases local light absorption in the pathology area. Due to typical asymmetry of the pathology development, the presence of asymmetry in the registered diaphanograms could be treated as an indicator of pathology development.
In order to automate the screening process, in this study we propose an approach to quantification of the registered diaphanograms based on correlation analysis. The processing of a diaphanogram consists in separation of the right and left parts of a face and futher calculation of the correlation coefficient between these images.
In the frames of the approach approbation, the correlation analysis was carried out for 21 conditionally healthy volunteers and 24 patients with maxillary sinus pathologies. Since two diaphanograms were recorded for each subject, 90 images were analyzed. The status of each patient was independently confirmed by results of CT and MRI studies. The analysis was performed for both probing wavelengths.
The obtained results showed that for the wavelength of 650 nm, the correlation coefficient was 0.903 ± 0.038 for conditionally healthy volunteers and 0.541 ± 0.233* for patients with pathologies. When using the wavelength of 850 nm, the correlation coefficient amounted 0.885 ± 0.047 and 0.582 ± 0.207* for healthy volunteers and patients respectively. A statistically significant difference (*) between the obtained values was confirmed at p < 0.05 according to the Mann-Whitney criterion.
Thus, the analysis of the asymmetry of the registered diaphanograms is a promising approach for detecting pathologies of the maxillary sinuses.
The study was funded by RFBR (research project № 20-32-90147).
Speaker
Ekaterina Bryanskaya
Orel State University named after I.S. Turgenev
Russia
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