Characteristics of photosensitizers from cyanoarylporphyrazines group: from viscosity sensitivity to immunogenic properties in photodynamic therapy of cancer
Tatiana A. Mishchenko1, Victoria D. Turubanova1, Maria Savyuk1, Irina V. Balalaeva1, Natalia Yu. Shilyagina1, Larisa G. Klapshina2, Svetlana A. Lermontova2, Maria V. Vedunova1 and Dmitri V. Krysko1,3,4
1Institute of Biology and Biomedicine, National Research Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russian Federation;
2G.A. Razuvaev Institute of Organometallic Chemistry of the Russian Academy of Sciences, Nizhny Novgorod, Russian Federation;
3Cell Death Investigation and Therapy Laboratory, Department of Human Structure and Repair, Ghent University, Ghent, Belgium;
4Cancer Research Institute Ghent, Ghent, Belgium.
Abstract
Photodynamic therapy (PDT) is a minimally invasive procedure that widely used in the therapy of different types of cancer. However, there is a still need to review and revise the current PDT approaches, in particular by creating of new photodynamic agents with improved photophysical and photobiological properties for boosting the PDT efficacy and maintaining the quality of patients’ lives.
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Tatiana Mishchenko
Lobachevsky State University of Nizhny Novgorod
Russia
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