Determination of the FSH level using microstructural waveguides
Yuliya D. Gudova,1, Julia S. Skibina,2, Alexey Yu. Gryaznov,2, Dmitry E. Gluhov,2 1 Saratov State University, Saratov, Russia 2 LLC SPE Nanostructured Glass Technology, Saratov, Russia
Abstract
Follicle-stimulating hormone (FSH) is a glycoprotein secreted by the adenohypophysis. FSH regulates the production of estrogen and stimulates the growth of ovarian follicles in the ovary. The determination of FSH in the blood is important for in vitro fertilisation (IVF), since its level determines the tactics of treatment and the preparation of a hormone therapy protocol.
At present, microstructural waveguides are considered as one of the most promising sensitive elements of optical waveguide sensors of physical quantities. It is possible to determine the level of sex hormones by using a device with a sensitive element based on microstructural waveguides. This method is distinguished by good repeatability and high sensitivity of the sensitive element to changes in the concentration of the test liquid.
The aim of the study is to improve the parameters and increase the accuracy of the method of determining the FSH level in blood serum using microstructural waveguides.
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Speaker
Yuliya D. Gudova
Saratov State University
Russia
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