OPTICAL CLEARING OF THE RAT SKIN EX VIVO BY GLYCEROL-DMSO SOLUTION IN THE SPECTRAL RANGE OF 350-2500 NM
Daria K. Tuchina,1,2 Nikita A. Navolokin,1,3 Valery V. Tuchin1,2,4
1Research-Educational Institute of Optics and Biophotonics, Saratov State University, Saratov, Russia
2Interdisciplinary Laboratory of Biophotonics, Tomsk State University, Tomsk, Russia
3Saratov State Medical University, Saratov, Russia
4Laboratory of Laser Diagnostics of Technical and Living Systems,Institute of Precision Mechanics and Control RAS, Saratov, Russia
Abstract
The experimental study was performed for ex vivo skin of white Wistar rats. Recording of diffuse reflectance and total transmission spectra of samples was carried out using a UV-3600 spectrophotometer with an integrating sphere (Shimadzu, Japan) in the spectral range of 350-2500 nm with a step width of 2 nm before and after immersion in 70%-glycerol solution with 10% of DMSO. Reduced scattering coefficient of samples was estimated. Transmission coefficient of the skin increased significantly after exposure of the tissue to the solution. Reduction in skin reflectance was observed. Significant decrease in the transport scattering coefficient was obtained.
This work was supported financially by the RF President Scholarship №СП-5422.2021.4.
Speaker
Daria Tuchina
Saratov State University
Russian Federation
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