Polarized light methods for probing sub-wavelength scale structural anisotropy
Nirmalya Ghosh, Nishkarsh, Jeeban K Nayak, Shubham Chandel, Subir Kumar Ray
Indian Institute of Science Education and Research (IISER) Kolkata
Abstract
In this talk I shall introduce some new experimental concepts of polarimetry for probing structural anisotropy of biological tissues and other complex materials at the nanometer (sub-wavelength) length scales. Specifically, a custom designed state-of-the-art dark-field spectroscopic Mueller matrix microscopy system will be discussed, which has the ability to extract complete polarization information and to quantify the intrinsic polarimetry characteristics from even a single isolated nanoparticle / nanostructure. An illustrative example of the exceptional ability of this system will be presented, where this polarization microscopic system in combination with a suitable polarization analysis model enabled quantitative assessment and understanding of the self-healing behavior of a bio-inspired piezoelectric organic crystal by sensing changes in structural anisotropy in the nanometer length scale. A spectral Mueller matrix based inverse light scattering polarimetry method for the quantification of nanometer scale multifractal (multi-scale self-similar) anisotropy of tissue will be presented and its initial application for pre-cancer detection will be discussed.
Relevant references
S. Bhunia et al, Science, 373 (6552), 321-327, (2021).
S.K. Ray et al, ACS Nano, 11, 1641-1648 ( 2017).
N. Modak et al, Phys. Rev. A 103, 053518 (2021).
S Samanta et al, Chemical Science, 11, 5710-5715 (2020).
BS Athira et al, Physical Review A 101 (1), 013836 (2020).
SK Ray et al, Physical Review A 100 (3), 033805 (2019).
N. Das et al, Laser Phys. Lett. 15 (3), 035601 (2018).
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Nirmalya Ghosh
IISER Kolkata
India
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