Brain activity functional analysis of the FMRI in MDD patients between Stroop and emotion tests
Vladimir S. Khorev,1,2 Semen A. Kurkin,2,3 Rositsa Paunova,4 Denitsa Semionova,4 Sevdalina Kandilarova,4 Drozdstoy S. Stoyanov,4
1 Innopolis University, Innopolis, Russia
2 Immanuel Kant Baltic Federal University, Kaliningrad, Russia
3 Samara State Medical University, Samara, Russia
4 Plovdiv Medical University, Plovdiv, Bulgaria
Abstract
In this work, we conducted the analysis of the functional magnetic resonance imaging data in patients with major depressive disorder that were obtained during experimental research when subjects are performing Stroop and emotion picture tests. The Stroop Color and Word test is widely used in clinical and experimental practice. In this study we decided to use this instrument in order to assess the ability to inhibit cognitive interference when two types of stimuli are coming at once. Words that are the names of colors appearing in the same or different color. Thus we have congruent stimuli: the word “red” in red and incongruent stimuli: the word “red” in yellow. In addition, an n-back component was added, and in the first part of the task, subjects were instructed to press a button every time the word was the same as the one two screens back. In the second part, the subjects had to press a button every time the color of the word was the same as the one two screens back (color condition). There were four consecutive 60 second blocks of each active condition (word and color) alternating with an off block (fixation cross) with a duration of 20 s. The signals that have undergone preprocessing and filtration were used to test the method of functional connectivity analysis to find the connections between the brain regions that demonstrate significant changes between functional tests.
File with abstract
Speaker
Vladimir Khorev
Innopolis University
Russia
Discussion
Ask question
