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ELECTROSPUN NANOFIBER SENSOR PLATFORM FOR DETERMINATION OF SOME BIOLOGICALLY ACTIVE COMPOUNDS

Tatyana M. Makhova, 1, Alexandra I. Danchuk, 1, Sergey Yu. Doronin, 1

1 Saratov State University, Russia

Abstract

Biologically active compounds, for example phenols or heavy metal ions could cause environmental pollution, which is a serious problem which can cause public health issues. Therefore, creation a sensitive, selective and simple method for determination of such components has proved to be extremely important. Electrospun nanofibrous membranes are nanostructures that possess large surface area, high porosity, good interconnected porous structure, and flexibility of surface functionalization are expected to be ideal candidates of substrates to improve the performance of the sensors; also, they are suitable for determination of different analytes. Combination of solid phase extraction of such toxicants by electrospun nanofibers (NFs) and their determination has a number of advantages, in particular, it is easy to use and cheap. In this study it was obtained polyacrylonitrile and polyamide electrospun NFs with the fiber diameter from 90 to 250 nm, contact angles from 53 to 92о, specific surface area from 33 to 41 cm2/g, and pore radii from 2.0 to 2,2 nm. Fourier-transform infrared spectroscopy (FTIR) was used to study electrospun nanofiber structure. Also, such methods were applied as spectrophotometry, diffuse reflectance spectroscopy, colorimetry to determine some biologically active substances.

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Danchuk Alexandra
Saratov State University
Russia

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