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In vivo OCT investigation of chemical enhance of the rat skin optical clearing by fructose solutions

Daria K. Tuchina,1,2 Alexey N. Bashkatov,1,2 Nikita A. Navolokin,1,3 Valery V. Tuchin1,2,4
1Saratov State University, Saratov, Russia; 2National Research Tomsk State University, Tomsk, Russia; 3Saratov State Medical University, Saratov, Russia; 4Institute of Precision Mechanics and Control RAS, Saratov, Russia

Abstract

The experimental study was performed for in vivo skin of white Wistar rats. The optical coherence tomography system, Spectral Radar OCT System OCP930SR 022 (Thorlabs Inc., USA) with a wavelength of 930 nm, was used for obtaining the quantitative data for effectiveness and rate of skin optical clearing at application of aqueous 50%-solution of fructose and aqueous-alcohol 50%-solution of fructose. The aqueous-alcohol 50%-solution of fructose showed more fast optical clearing but the same optical clearing effect of rat skin compare to fructose solution without alcohol.

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Daria Tuchina
Saratov State University
Russia

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