Rigorous full-wave description of OCT-scan formation based on ballistic scattering of arbitrary-profile beams for simulation of multimodal OCT

Abstract

We present a computationally efficient full-wave spectral model of OCT-scan formation with the following capabilities/features: (i) arbitrary phase-amplitude profile of illuminating beams; (ii) absence of paraxial approximation; (iii) broadly used approximation of ballistic scattering by discrete scatterers without additional limitations on their density/location and scattering strength; (iv) factors describing the wave decay, (v) measurement noises with given signal-to-noise ratios and (vi) arbitrary inter-scan displacements of scatterers are easily introducible. The model is computationally efficient due to the use of rapid summations and fast Fourier-transforms. Main model features are illustrated, including comparative simulations of OCT scans for Bessel versus Gaussian beams, presence of arbitrary aberrations at the tissue boundary and various scatterer motions. The unprecedented flexibility and computational efficacy of the model allow one to accurately study various properties of OCT-scans for developing new methods of their processing in various biomedical applications.

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Speaker

Lev A. Matveev
Federal research center Institute of Applied Physics of the Russian Academy of Sciences
Russia

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