Stimulation of heart pacemakers cells using pulsed infrared radiation
Mohammad Ali Ansari, 1 Hassan Tajarenejad, 1 Soheila Akbari, 1 Seyedeh Mehri Hamidi, 1
1 Laser and plasma research institute, Shahid Beheshti University, Tehran, Iran.
Abstract
Optical Pacing (OP) has shown to be a feasible non-invasive alternative to electrical pacing in recent years. Infrared lasers may be useful for this approach because of the absorption properties of infrared light in biological tissue. As a result, the idea of this research is to investigate how IR radiation affects the temperature of cardiac pacemaker cells. To study optimal heart cell stimulation parameters, we first investigate heat production and temperature increases caused by IR pulses in heart tissues as a function of pulse length and radiant radiation exposure. Then, the toad heart is then treated with pulsed infrared lasers in an experiment (1450 and 1550 nm). By monitoring the toad's heart rhythm, the temperature effect of IR radiation on its cardiac pacemaker cells is studied. The findings demonstrate that the thermal action of IR pulses raises the intracellular calcium ion level in cardiac cells in response to variations in the amplitude of ECG waves. In conclusion, the results show that non-invasive IR pulses may successfully activate cardiac pacemaker cells.
Speaker
Mohammad Ali Ansari
Laser and Plasma Research Institute, Shahid Beheshti University
Iran
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