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Sensitivity and specificity of OCR in OME diagnostics

Anait L. Dilenyan, 1,2 Pavel A. Shilyagin,2 Daria D. Smirnova,1 Polina V. Bazan,1 Alexander A. Moiseev,2 Dmitrii A. Terpelov,2 Sergey.Yu. Ksenofontov,2 Alexey A. Novozhilov, 1,2
1 Privolzhsky region medical centre, Nizhny Novgorod, Russia
2 Institute oa applied physics of RAS, Nizhny Novgorod, Russia

Abstract

Objective. To determine the efficiency of using an optical coherence tomography (OCT) and a new method for evaluating recorded images for detecting and differentiating middle ear effusions (MEEs).

Study Design. Cross-sectional study.

Setting. POMC (Volga District Medical Center)

Subjects and Methods. Sixteen adults patients undergoing tympanostomy tube placement were preoperatively imaged using an OCT device . Eigteen OCT data subset of MEE from these patients and eight of healthy volunteers were included in a blinded reader quiz via specially designed viewer program AnalysEar . It was conducted using 24 readers from 3 groups of tiered medical expertise. The primary outcome assessed was reader ability to detect presence/absence of MEE. A secondary outcome assessed was reader ability to differentiate serous vs nonserous MEE.

Results. Blinded reader analysis of an OCT data subset for detection of MEE resulted in 95.7% accuracy, 98.1% sensitivity, 90.3% specificity, and interreader agreement of 93.4%. Differentiating MEE type, reader identification of nonserous MEE had 90.6% accuracy, 85.7% sensitivity, 94% specificity, and interreader agreement of 91%. We especially want to highlight the OCT-experienced group that has showed accuracy, sensitivity and specificity of detection of MEE at the level of 99,6%, 99,4%, and 100%, respectively.

Conclusion. OCTotoscopy shows promise for facilitating accurate MEE detection. The imageability of using viewer program AnalysEar displays significant results not only with detection of MEE but also with identification of nonserous MEE.

Speaker

Anait L. Dilenyan
Anait 1 Privolzhsky region medical centre, Nizhny Novgorod, Russia 2 Institute oa applied physics of RAS, Nizhny Novgorod, Russia
Russia

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