Biomedical Optoacoustics: From Idea to Imaging and Therapy

Abstract

We proposed optoacoustics (photoacoustics) for biomedical diagnostic applications in late 80s – early 90s. At present, the optoacoustic technique is an emerging diagnostic modality which combines high optical contrast and ultrasound spatial resolution. This technique is based on generation of optoacoustic waves using short optical pulses and allows for high-resolution molecular imaging in tissues. We demonstrated in pre-clinical and clinical studies optoacoustic detection and imaging of tumors, monitoring of thermotherapy (hyperthermia, coagulation, freezing), monitoring of cerebral blood oxygenation in patients with traumatic brain injury, neonatal patients, fetuses, central venous oxygenation monitoring, hematoma detection, and transcranial brain imaging. Recently, we proposed to use optoacoustics for noninvasive therapy and theranostics and demonstrated efficacy of this technique in vivo.

Speaker

Rinat O. Esenaliev, PhD
University of Texas Medical Branch
USA

Discussion

Ask question