Study of the effectiveness of aqueous dispersion of gold nanoparticles as a potential photosensitizer for photodynamic antimicrobial therapy
Olga V. Nechaeva 1, Tatiana A. Shulgina 2, Elena V. Glinskaya 3, Ksenia V. Zubova 3, Dmitry A. Shnaider 4, Natalya V. Bespalova 1
1 Saratov State Technical University, Saratov, Russia, 2 Institute of Traumatology and Orthopedics, Saratov Medical State University, Saratov, Russia, 3 Saratov State University, Saratov, Russia, 4 Saratov State Medical University, Saratov, Russia
Abstract
A high antimicrobial activity of an aqueous dispersion of gold nanoparticles stabilized with polyvinyl alcohol was established during photodynamic antimicrobial therapy of experimental purulent wounds. The results obtained allow us to consider it as a promising and safe photosensitizer for photodynamic antimicrobial therapy of infectious lesions of the skin and soft tissues.
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Olga V. Nechaeva
Saratov State Technical University
Russia
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