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Differentiation of Lumpy Skin Disease Virus and Sheeppox Virus strains using of GB-speckles, generated for the nucleotide sequences of the gene GPCR

Yury Saltykov1, Anna Kolosova1, Sergey Ulyanov1,2, Onega Ulianova2, Valentina Feodorova1.
1Federal Research Center for Virology and Microbiology, Branch in Saratov, Russia; 2Department of Medical Physics, Saratov State University, Saratov, Russia

Abstract

The nucleotide sequences of the GPCR gene of Lumpy Skin Disease Virus (LSDV) and Sheeppox Virus (SPPV) strains have been transformed into 2D realizations of GB-speckles (Gene-Based speckles). Based on the analysis of statistical properties of corresponding GB-speckles, a possibility of differentiation between wild-type/vaccines LSDV and SPPV strains which could be used as heterologous vaccines against Lumpy Skin Disease has been shown. It has been demonstrated that an application of the GB-speckles has the great perspectives from viewpoint of modern bioinformatics.

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Yury Saltykov
Federal Research Center for Virology and Microbiology, Branch in Saratov, Russia
Russia

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