Frequency-dependent FDTD study of SAR distribution in the skin for the enhanced Microwave treatment of cancer
Mohammad Ali Ansari, 1 Shayan Dodge, 1 Mahshad Hajian, 1 Alireza Niknam,1
1 Laser and Plasma Research Institute, Shahid Beheshti University, Tehran, Iran.
Abstract
Microwave thermal therapy is a type of cancer treatment in which malignant tissue temperature under the influence of microwave is increased to kill cancer cells with little or no harm to normal tissue; hence computational techniques continue to evolve to improve the efficiency of this therapy. This paper proposes the frequency-dependent finite-difference-time-domain (FDTD) method to investigate the frequency dependence of normal and malignant skin absorption rates under the influence of microwave pulse. Given that the physical characteristics of the biological tissue are highly dependent on frequency; therefore, the Cole-Cole model is considered to estimate frequency dependence of biological tissue under exposure to a microwave pulse in the FDTD method. In addition, the frequency-dependent specific absorption rate (SAR) distribution in the three-layer normal and malignant skin is computed to select the resonance frequency in malignant skin. Finally, the results show that the malignant tissue can be destroyed by selecting the appropriate microwave parameters.
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Mohammad Ali Ansari
Laser and Plasma Research Institute, Shahid Beheshti University
Iran
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