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OPTO-THERMO-ACOUSTIC STUDIES FOR CANCER DIAGNOSIS

UTTAM M. PAL AND HARDIK J. PANDYA
Department of Electronic Systems Engineering, Division of EECS, Indian Institute of Science, Bangalore
hjpandya@iisc.ac.in

Abstract

Breast cancer is the leading cause of mortality for women accounting for around 6.9% of breast cancer-related deaths worldwide in 2020. If the results from X-Ray mammography and sonography of the patients are found to be suspicious, they are recommended for histopathology test to confirm a breast cancer diagnosis. Histopathology is considered a gold standard; however, it is time-consuming and requires skilled personnel [1]. A multimodal system that can characterize the bulk optical, thermal, and acoustic properties of the tissue is designed and developed. The measurements were carried out on ex-vivo breast biopsy tissues from N = 44 patients, and it was observed that the reduced scattering coefficient and acoustic attenuation of the malignant tissue were higher than the adjacent normal tissues. In contrast, an opposite trend was ascertained for the thermal conductivity. The highest statistical significance was observed when the combined reduced scattering coefficient, thermal conductivity, and acoustic attenuation measurements were considered [2-4].

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Speaker

HARDIK JEETENDRA PANDYA
Professor
India

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