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Temperature determination of biological tissues various types from the luminescence spectrum of upconversion nanoparticles through a biological tissue layer with intravenous administration of nanoparticles

Natalia I. Kazadaeva1, Anna A. Doronkina1, Ekaterina A. Kozlova1, Irina Yu. Yanina1, Alexander A. Skaptsov1, Yulia G. Konyukhova1, Alexander B. Pravdin1, Artyom M. Mylnikov2, Nikita A. Navolokin3, Vyacheslav I. Kochubey1 1 Saratov State University, Saratov, Russia, 2 Saratov State Medical University, Saratov, Russia

Abstract

Upconversion nanoparticles can be used to determine the temperature in biological objects. In this work, we are research the dependence of biological tissue temperature determination error from the luminescence of upconversion nanoparticles through a biological tissue layer on the type of biological tissue, intravenous administration of nanoparticles, and the depth of nanoparticles in biological tissue. Attenuation of light wield major influence on biological tissue temperature determination error. Scattering prevails in the exsanguinated biological tissue, which leads to positive values of the error. Absorption has a significant advantage in the blood-filled tissue, and the error becomes negative.
The work was carried out under the financial support from the Russian Science Foundation (project No. 19-12-00118)

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Kazadaeva Natalia
Saratov State University
Russia

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