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Raman scattering spectra postprocessing and decomposition to assess the glial tumor border

A.V. Orlov,1 T.A. Savelieva,1,2 I.D. Romanishkin,2 B.A. Tsarukaev,3 A.V. Kosyrkova,3 S.V. Shugaj,3 S.A. Goryajnov,3 V.B. Loschenov,1,2
1 National Research Nuclear University MEPhI, Kashirskoe Highway 31, 115409, Moscow, Russia 2 Prokhorov General Physics Institute of the Russian Academy of Sciences, Vavilova 38, 119991, Moscow, Russia 3 N.N. Burdenko National Medical Research Center of Neurosurgery, Moscow, Russia

Abstract

Brain tumors such as gliomas, and especially glioblastomas, are most hard ones to determine the borders and surgically remove. The aim of this work was to determine the most informative regions of the Raman spectrum when analyzing tissues in the operating room immediately after removal.

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Arseniy Orlov
National Research Nuclear University MEPhI
Russia

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