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Development of pellets for studying the diabetic blood plasma in the THz frequency range

Lykina A.A.1, Nazarov M.M.2, Konnikova M.R.3,4, Trukhin V.N.5, Gavrilova P.G.1,5, Vaks V.L.6, Anfertyev V.A.6, Domracheva E.G.6, Chernyaeva M.B.6, Kistenev Yu.V.7,Vrazhnov D.A.8, Prischepa V.V.7, Kononova Yu.A.9, Korolev D.V.9, Toropova Ya.G.9, Cherkasova O.P.3,10, Shkurinov A.P.3,4, Smolyanskaya O.A.1


1 ITMO University, Saint-Petersburg, Russia
2 National Research Center "Kurchatov Institute", Moscow, Russia
3 Institute on Laser and Information Technologies of RAS, Branch of the FSRC “Crystallography and Photonics”, RAS, Shatura, Moscow Region, Russia
4 Department of Physics and International Laser Center, Lomonosov Moscow State University, Moscow, Russia
5 A.F. Ioffe Physical-Technical Institute RAS, Saint-Petersburg, Russia
6 Institute for Physics of Microstructures RAS, Nizhny Novgorod, Russia
7 Tomsk State University, Tomsk, Russia
8 Institute of Strength Physics and Materials Science SB RAS, Tomsk, Russia
9 Almazov National Medical Research Centre, Saint-Petersburg, Russia
10 Institute of Laser Physics of SB RAS, Novosibirsk, Russia

Abstract

This work is devoted to the development of a suitable phantom of a biological object for measurements in the THz frequency range and for approbation with various diagnostic methods developed in different THz laboratories. The phantoms were represented as a pellet of human blood plasma in the diabetic and the control groups. These objects were analyzed in various laboratories, using THz pulsed spectroscopy. Analysis of the THz spectra was carried out using the principal component analysis (PCA) to differentiate the spectral features between the diabetic and control groups. The reported study was funded by RFBR according to the research project #17-00-00275 (#17-00-00270, #17-00-00272, #17-00-00184, #17-00-00186) and by the Government of the Russian Federation (Grant 08-08).

Speaker

A.A. Lykina
ITMO University
Russia

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