Dielectric properties of blood serum with liver cancer in THz frequency range
M.R. Konnikova1, M.M. Nazarov2, O.P. Cherkasova1, 3, E.N. Lazareva4, 5,
P.A. Dyachenko4, 5, V.V. Tuchin4, 5, 6, A.P. Shkurinov1, 7
1 Institute for Problems of Laser and Information Technologies of the Russian Academy of Sciences, Branch of FSRC Crystallography and Photonics, Russia
2 National Research Centre Kurchatov Institute, Russia
3 Institute of Laser Physics, Siberian Branch, Russian Academy of Sciences, Russia
4 Tomsk State University, Russia
5 Saratov State University, Russia
6 nstitute of Precision Mechanics and Control, Russian Academy of Sciences, Russia
7 Lomonosov Moscow State University, Russia
Abstract
The main THz marker in biological tissues and fluids is water, which can be in free and bound states. Each of these states is characterized by its own relaxation time, which contributes to the absorption spectrum exactly in the THz and sub-THz frequency ranges. In this study the influence of bound water on the THz response of healthy rats and in experimental liver cancer 28 days after tumor injection. Various components of blood may have a significant impact on its optical properties, as a result of which the development of pathological conditions causes a change in the total dielectric constant. THz spectroscopy is an additional method for analyzing the dielectric properties of biological fluids to the IR range.
Speaker
Olga Cherkasova
Institute of Laser Physics of the Siberian Branch of the RAS
Russia
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