Diagnosis of glioma molecular markers by terahertz spectroscopy
O.P. Cherkasova1.2
1Institute of Laser Physics, Siberian Branch of the RAS, Russia
2Institute on Laser and Information Technologies - Branch of the Federal Scientific Research Centre "Crystallography and Photonics" of RAS, Shatura, Moscow Region, Russia
Abstract
Gliomas are invasive brain tumors with high rates of recurrence and mortality. One of the main directions of diagnostics and treatment of malignant tumors is investigation of the reasons of formation and the routes of the generation of cancer molecular markers for the elaboration of new methods of early diagnostics and therapy. It has been recently shown that one of specific markers for glioma differential diagnostics are enantiomers of 2-hydroxyglutarate (L-2HG and D-2HG) in brain tissues and blood. The paper presents the results of a study of the most probable glioma molecular markers by the terahertz time-domain spectroscopy.
The work was supported by the RFBR and National Natural Science Foundation of China, research project № 19-52-55004.
Speaker
Olga Cherkasova
Institute of Laser Physics of the Siberian Branch of the RAS
Russia
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