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A photoacoustic monitoring of circulating tumor cells in mice with melanoma.

Oleg Grishin [1], Arkadii Abdurashitov [2], Nataliya Shushunova [1], Roman Verkhovskii [1], Evgenii Shashkov [3], Daniil Bratashov [1], Vladimir P. Zharov [4], Olga Inozemtseva [1]

1 – Saratov State University, Saratov, Russia
2 – Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Moscow, Russia
3 – Prokhorov General Physics Institute of RAS, Moscow, Russia
4 – University of Arkansas for Medical Sciences, Little Rock, AR, USA

Abstract

Сirculating tumor cells (CTCs) are cancer cells that have entered a blood or lymph stream from a primary tumor or its metastasis. In this work we demonstrate results of a three-week monitoring of CTCs in mice with a melanoma induced by B16F10 cell inoculation. The monitoring was performed using a custom photoacoustic flow cytometer (PAFC) adapted for mice.
This work was supported by the RF grant 14.Z50.31.0044.

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Grishin Oleg
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