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Comparative OCT study of optical clearing of human skin in vivo with phototypes II and VI

Isabella A. Serebryakova1, Yury I. Surkov1, Elina A. Genina1,2, Alexey N. Bashkatov1,2, Valery V. Tuchin1,2,3, and Vladimir Zharov4
1. Saratov State University, Saratov, Russia
2. Tomsk State University, Tomsk, Russia
3. Institute of Precision Mechanics and Control of the Russian Academy of Sciences, Saratov, Russia
4. Arkansas Nanomedicine Center, University of Arkansas for Medical Sciences, Little Rock, AR USA


We present the results of an experimental study of the novel approach: Microdermabrasion, Oleic acid and UltraSound Effect (MOUSE) on the probing depth of optical coherence tomography of human skin with phototypes II and VI. Optical coherence tomography (OCT) was used for skin monitoring during an hour. The obtained results indicate a significant increase in the depth of OCT optical probing for both light and highly pigmented skin. The efficiency of optical clearing using this approach was 32 ± 1.8% and 20.7 ± 1.6% for skin of II and VI phototypes, respectively.


Isabella Serebryakova
Saratov State University


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