SARATOV FALL MEETING SFM 

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Determination of male reproductive function using microstructural waveguides

Sukhih Gennady T., Director of Research Center for Obstetrics, Gynecology and
Perinatology, Professor, MD, PhD
4 Oparin str, 117997, Moscow, Russia
E-mail: g_sukhikh@oparina4.ru

Skibina Julia Sergeevna, Ph.D. in physics and mathematics, Director of LLC SPE
“Nanostructed Glass Technology” and Deputy Director of International Research and
Education Center “Structural Nanobiophotonics”
Address: 410033, Russia, Saratov, pr. 50 let Octyabrya, 101, room III (PO Box
2985).
E-mail: director@nano-glass.ru

Zanishevskaya Anastasia Andreevna - Senior Research Fellow in LLC SPE
“Nanostructed Glass Technology”, Head of the Advanced Research Department of
International Research and Education Center “Structural Nanobiophotonics”
Address: 410033, Russia, Saratov, pr. 50 let Octyabrya, 101, room III (PO Box
2985).
E-mail: zanishevskayaaa@nano-glass.ru

Shuvalov Andrey Alexandrovich - Deputy Head of Research Department in LLC
SPE “Nanostructed Glass Technology”, International Research and Education Center
“Structural Nanobiophotonics”
Address: 410033, Russia, Saratov, pr. 50 let Octyabrya, 101, room III (PO Box2985).
E-mail: shuvalovaa@nano-glass.ru

Yanchuk Natalia Olegovna, Ph.D. in medical sciences, Head of the Sensor
Technology Department in International Research and Education Center “Structural
Nanobiophotonics”
Address: 410033, Russia, Saratov, pr. 50 let Octyabrya, 101, room III (PO Box
2985).
E-mail: info@nano-glass.ru

Gryaznov Aleksey Yuryevich, Leading Researcher in LLC SPE “Nanostructed
Glass Technology”, Head of the Department of Decision Support Systems in
International Research and Education Center “Structural Nanobiophotonics”.
Address: 410033, Russia, Saratov, pr. 50 let Octyabrya, 101, room III (PO Box
2985).
E-mail: info@nano-glass.ru

Sysoeva Anastasia, Embryologist of ART Department, Research Center for Obstetrics,
Gynecology and Perinatology, Ministry of Health of the Russian Federation.
117997, Russia, Moscow, Ac. Oparina str. 4
E-mail: sysoeva.a.p@gmail.com

Makarova Nataliya Petrovna, PhD, Researcher of ART Department, Research Center
for Obstetrics, Gynecology and Perinatology, Ministry of Health of the Russian
Federation.
117997, Russia, Moscow, Ac. Oparina str. 4
E-mail: np_makarova@oparina4.ru

Kalinina Elena Anatolievna, M.D., Ph.D., Head of IVF Department
Research Center for Obstetrics, Gynecology and Perinatology
4 Oparin str, 117997, Moscow, Russia
E-mail: e_kalinina@oparina4.ru

Abstract

Objective
The diagnosis of male infertility, especially idiopathic, remains ineffective: there areno standard tests for assessing fertility. To solve this problem, the development of an integrated system based on microstructure waveguides and artificial intelligence is proposed.
Design
Using spectral characteristics of seminal plasma and human ejaculate, obtained with use of microstructure waveguides, to evaluate sperm quality by means of neural networks
Setting
Public hospital; Scientific and Industrial Private Enterprise
Patients
345 samples of ejaculate and 209 sample of seminal plasma were obtained in which the volume of ejaculate corresponded to the norm (WHO, 2010)
Interventions
None.
Main outcome measures Spermogram (concentration, motility and morphology). The spectral characteristics of samples of seminal plasma and human ejaculate, obtained using microstructure waveguides.
Results
According to the minimum reference values of ejaculate indicators, the samples of ejaculate and seminal plasma were divided into 2 groups: “normal” and “pathology”. The spectral characteristics of samples of seminal plasma and human ejaculate are used as input parameters for constructing machine learning models. The neural network showed 100% accuracy.
Conclusion
Preliminary results obtained in this work, including the analysis of seminal plasma and/or ejaculate of 350 men, show the high promise of the proposed method of semen quality assessment which can be used in place of or in addition to standard techniques.

Speaker

Lepilin Pavel Andreevich
LLC SPE “Nanostructed Glass Technology”, International Research and Education Center “Structural Nanobiophotonics”
Россия

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