Petal-like Gap-enhanced Raman Tags with a Controllable Structure
Boris Khlebtsov, IBPPM RAS
Andrey Burov, IBPPM RAS
Daniil Bratashov, Saratov State University
Roman Tumskiy, IBPPM RAS
Nikolai Khlebtsov, IBPPM RAS, Saratov State University
Abstract
Surface-enhanced Raman scattering tags show promising potential for in vitro and in vivo bioimaging applications due to lack of photobleaching and narrow spectral lines. However, reproducible and controllable growth of nanostructures with a high density of hot-spots is still a challenge. We report on an improved strategy for the synthesis of core/shell Raman tags with a high density of hot-spots from petal-like shell structures and a high-rate immobilization of reporter molecules. Various types of particles were obtained including gap-enhanced Raman tags (GERTs) with a solid shell, petal-like GERTs, porous Au particles filled with Raman molecules. Optimized petal-like tags (p-GERTs) demonstrate a SERS response 50 times higher than usual gap-enhanced Raman tags, which make them suitable for spectroscopy at the single-particle level.
Speaker
Boris Khlebtsov
IBPPM RAS
Россия
Discussion
Ask question
