NUMERICAL SIMULATION IN OPTICAL COHERENCE TOMOGRAPHY AS A TOOL FOR DEVELOPMENT OF EMERGING OCT-MODALITIES
Theoretical modeling and numerical simulations of signal formation in optical coherence tomography (OCT) is a useful tool for understanding and evaluation of the actively developing novel modalities in OCT including, but not limited to elastography, angiography and digital refocusing. In real tissues and physical phantom experiments the fine control of scatterers parameters are complicated, therefore the numerical simulations are preferable. Numerical simulation of OCT signals allows to simulate highly controllable parameters of the tissue properties, e.g. position of the scatterers, its scattering properties and evolution of the scatterer positions (due strain, Brownian motions or flows). We develop full-wave model for simulations of scans in OCT and modify this model with accounting for beam focusing and the motion of scatterers. In this report we demonstrate how the developed full-wave model can be used for phase-sensitive OCT signal formation and processing evaluation. Based on this model we evaluate several algorithms of OCT signal processing for strain mapping, angiography and numerical refocusing.
Institute of Applied Physics of the Russian Academy of Sciences
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