Breakthrough strategies of stimulation of the cerebral lymphatics during sleep
Nikita Navolokin, Saratov State University, Russia; Alexander Shirokov, Saratov State University, Russia; Ivan Fedosov, Saratov State University, Russia; Maria Klimova, Saratov State University, Russia; Andrey Terskov, Saratov State University, Russia; Aysel Mamedova, Saratov State University, Russia; Inna Blokhina, Saratov State University, Russia; Nikita Lezhnev, Saratov State University, Russia; Ilana Agranovich, Saratov State University, Russia; Oxana Semyachkina-Glushkovskaya, Saratov State University, Russia
Abstract
There is intensive grow body of evidance that the sleep and lymphatics plays an crucial role in the keeping the health of the central nervous system (CNS) via the nigth activation of drainage of CNS tissues and clearance of metabolites and neurotoxins. Sleep can be the natural factor for activation of the cerebral lymphatics. The ability to stimulate the lymph flow in sleep brain, is likely to play an important role in developing the promising methods in neurorehabilitation therapy. However, the scanty information available about mechanisms of lymphatic clearance of waste products and toxins from the brain. It slows down progress in the apperance of technologies for therapeutic modulations of the lymphatics in the CNS. In this study we demonstrate the results, which worrent a revision of our knowledge about the anatomy and physiology of the cerebral lymphatics and an innovative stratagies in night stimulation of the cerebral lymphatics as a breakhtrough technologies for the clearance of macromolecules and toxins from the brain.
Speaker
Semyachkina-Glushkovskaya Oxana
Saratov State University
Russia
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