SARATOV FALL MEETING SFM 

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computational optical clearing to in-vivio estimate hidden chromophore content

M.A.Ansari
Laser and Plasma Research Institute,
Shahid Beheshti University, Tehran, Iran

V.V.Tuchin
Department of Optics and Biophotonics,
Saratov State University, Saratov, Russia;
Laboratory of Laser Diagnostics of
Technical and Living Systems, Institute of
Precision Mechanics and Control of the
RAS, Saratov, Russia;
Interdisciplinary Laboratory of
Biophotonics, Tomsk State University,
Tomsk, Russia;

Abstract

Recently, a new optical clearing (OC) method called computational OC (based on diffusion equation) has been presented. This
OC method applies diffuse reflectance spectroscopic data to estimate distribution of particular chromophores of interest hidden on the background of absorption of blood,
melanin and water without applying any inverse methods. This method offers a fast and low-cost method to measure the content of choromophores inside skin which opens a new way for personal medicine.
Here, we apply this method to estimate melanin and carotenoids inside the skin of the palm.

Speaker

Mohammad Ali Ansari
Laser and Plasma Research Institute, Shahid Beheshti University
Iran

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