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The GB-speckles generated for the gene pgp4 as the promissing model towards to differentiation some Chlamydia spp.

Maria Khizhnyakova, Federal Research Center for Virology and Microbiology, Branch in Saratov, Russia
Sergey Zaitsev, Federal Research Center for Virology and Microbiology, Branch in Saratov, Russia
Yuriy Saltykov, Federal Research Center for Virology and Microbiology, Branch in Saratov, Russia
Onega Ulianova, Department of Medical Physics, Saratov State University, Saratov, Russia
Sergey Ulyanov, Federal Research Center for Virology and Microbiology, Branch in Saratov, Russia, Department of Medical Physics, Saratov State University, Saratov, Russia
Alexander Ulyanov, Rocolabs, 27 West 24th Street Suite 704, New York, NY, 10010
Valentina Feodorova, Federal Research Center for Virology and Microbiology, Branch in Saratov, Russia

Abstract

Chlamydiaceae family is consisted of intracellular bacteria pathogenic for both humans and animals. In this paper the nucleotide sequences of the gene encoding Pgp4 protein, the well-known virulence factor in Chlamydia, have been successfully transformed into the form of the GB-speckles. Strong discrimination was found between the relevant speckle patterns derived from three Chlamydiae spp., namely Chlamydia psittaci, Chlamydia abortus and Chlamydia trachomatis.

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Maria Khizhnyakova
Federal Research Center for Virology and Microbiology, Branch in Saratov, Russia
Russia

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