The GB-speckles generated for the gene pgp4 as the promissing model towards to differentiation some Chlamydia spp.
Chlamydiaceae family is consisted of intracellular bacteria pathogenic for both humans and animals. In this paper the nucleotide sequences of the gene encoding Pgp4 protein, the well-known virulence factor in Chlamydia, have been successfully transformed into the form of the GB-speckles. Strong discrimination was found between the relevant speckle patterns derived from three Chlamydiae spp., namely Chlamydia psittaci, Chlamydia abortus and Chlamydia trachomatis.
Federal Research Center for Virology and Microbiology, Branch in Saratov, Russia
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