Absence epileptiform activity simulation using a nonautonomous network of neural-like radioengineering circuits

Abstract

In this paper, we simulate the electrical activity
of the brain thalamocortical network using an ensemble of small number of
electrical circuits which are radioengineering realizations of
FitzHugh-Nagumo neuron model. We investigate oscillatory
regimes both in the autonomous network, and in the network
driven by another similar model FitzHugh-Nagumo neuron representing external
input from nervus trigeminus. We show that the long transient processes in response to relatively short external driving are possible in the ensemble, which are absent in the individual neuronal oscillators. These transients can be considered as a model of spike-wave discharge, which is the main manifestation of absence seizures.

Speaker

Egorov N.
Saratov Branch of Kotelnikov Institute of Radioengineering and Electronics of Russian Academy of Sciences
Russia

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